Avaliação do Tópico:
  • 0 Voto(s) - 0 em Média
  • 1
  • 2
  • 3
  • 4
  • 5
buy my weed online reddit politics discussion forum
#1
buy my weed online reddit politics discussion forum

We offer CBD Hemp related products providing the best potencies and purity of Cannabidiol (CBD) products available nationwide. Our mission is to educate and promote natural therapies as part of our approach to optimum health and wellness. We have various products to suit the multiple needs and conditions of our clients.

[Imagem: Buy-Now-Button.png]

===>Delivery of the product to all states of America<===

[Imagem: 15864.png]

"Cannabidiol: Barriers to Research and Potential Medical Benefits"

Mr. Chairman, Ms. Chairwoman, and Members of the Senate Drug Caucus, thank you for inviting the National Institute on Drug Abuse (NIDA), a component of the National Institutes of Health (NIH), to participate in this hearing to share what we know about the biology and the potential therapeutic effects of cannabidiol (CBD), one of the main active chemical compounds found in marijuana. In light of the rapidly evolving interest in the potential use of marijuana and its derivative compounds for medical purposes, it is important to take stock of what we know and do not know about the therapeutic potential of CBD.

[Imagem: Cibdex-All-products-300x242.png]

Background

To date, 23 states and the District of Columbia have passed laws allowing marijuana to be used for a variety of medical conditions. Fifteen additional states have enacted laws intended to allow access to CBD oil and/or high-CBD strains of marijuana. Interest in the potential therapeutic effects of CBD has been growing rapidly, partially in response to media attention surrounding the use of CBD oil in young children with intractable seizure disorders including Dravet syndrome and Lennox-Gastaut syndrome. While there are promising preliminary data, the scientific literature is currently insufficient to either prove or disprove the efficacy and safety of CBD in patients with epilepsy.i and further clinical evaluation is warranted. In addition to epilepsy, the therapeutic potential of CBD is currently being explored for a number of indications including anxiety disorders, substance use disorders, schizophrenia, cancer, pain, inflammatory diseases and others. My testimony will provide an overview of what the science tells us about the therapeutic potential of CBD and of the ongoing research supported by NIH in this area.
CBD Biology and Therapeutic Rationale


[Imagem: 15862.png]

Neuroprotective and Anti-Inflammatory Effects

CBD has also been shown to have neuroprotective properties in cell cultures as well as in animal models of several neurodegenerative diseases, including Alzheimer’s,xii,xiii,xiv stroke,xv glutamate toxicity,xvi multiple sclerosis (MS),xvii Parkinson’s disease,xviii and neurodegeneration caused by alcohol abuse.xix Nabiximols (trade name Sativex), which contains THC and CBD in roughly equal proportions, has been approved throughout most of Europe and in a number of other countries for the treatment of spasticity associated with MS. It has not been approved in the United States, but clinical trials are ongoing, and two recent studies reported that nabiximols reduced the severity of spasticity in MS patients.xx,xxi There have been limited clinical trials to assess the potential efficacy of CBD for the other indications highlighted; however, a recent small double-blind trial in patients with Parkinson’s disease found the CBD improved quality-of-life scores.xxii

Analgesic Effects

There have been multiple clinical trials demonstrating the efficacy of nabiximols on central and peripheral neuropathic pain, rheumatoid arthritis, and cancer pain.xxiii In addition, nabiximols is currently approved in Canada for the treatment of central neuropathic pain in MS and cancer pain unresponsive to opioid therapy. However, the current evidence suggests that the analgesia is mediated by THC and it is unclear whether CBD contributes to the therapeutic effects.xxiv THC alone has been shown to reduce pain;xxv,xxvi we are unaware of clinical studies that have explored the efficacy of CBD alone on pain. However, the anti-inflammatory properties of CBD (discussed above) could be predicted to play a role in the analgesic effects of nabiximols. Recent research has also suggested that cannabinoids and opioids have different mechanisms for reducing pain and that their effects may be additive, which suggests that combination therapies may be developed that may have reduced risks compared to current opioid therapies. However, this work is very preliminary.xxvii

Anti-Tumor Effects

In addition to the research on the use of cannabinoids in palliative treatments for cancer—reducing pain and nausea and in increasing appetite—there are also several pre-clinical reports showing anti-tumor effects of CBD in cell culture and in animal models.xxviii These studies have found reduced cell viability, increased cancer cell death, decreased tumor growth, and inhibition of metastasis (reviewed in McAllister et al, 2015).xxix These effects may be due to the antioxidant and anti-inflammatory effects of CBD;xxx however these findings have not yet been explored in human patients. There are multiple industry sponsored clinical trials underway to begin to test the efficacy of CBD in human cancer patients.

Anti-Psychotic Effects

Marijuana can produce acute psychotic episodes at high doses, and several studies have linked marijuana use to increased risk for chronic psychosis in individuals with specific genetic risk factors. Research suggests that these effects are mediated by THC, and it has been suggested that CBD may mitigate these effects.xxxi There have been a few small-scale clinical trials in which patients with psychotic symptoms were treated with CBD, including case reports of patients with schizophrenia that reported conflicting results; a small case study in patients with Parkinson’s disease with psychosis, which reported positive results; and one small randomized clinical trial reporting clinical improvement in patients with schizophrenia treated with CBD.xxxii Large randomized clinical trials would be needed to fully evaluate the therapeutic potential of CBD for patients with schizophrenia and other forms of psychosis.

[Imagem: How-CBD-Oil-can-be-used-CBD-Hemp-Oil-Benefits.jpg]

The problem is, CBD oil, capsules, powders, etc. are not easily absorbed by your body. They can spoil and become contaminated. They smell bad. They often ...
CBD is the abbreviation for cannabidiol, this is a non-psychoactive cannabinoid which can be found in the cannabis plant. Buy CBD Oil Here!

[Imagem: Visit-Website-Button.png]

Anti-Anxiety Effects

CBD has shown therapeutic efficacy in a range of animal models of anxiety and stress, reducing both behavioral and physiological (e.g., heart rate) measures of stress and anxiety.xxxiii,xxxiv In addition, CBD has shown efficacy in small human laboratory and clinical trials. CBD reduced anxiety in patients with social anxiety subjected to a stressful public speaking task.xxxv In a laboratory protocol designed to model post-traumatic stress disorders, CBD improved “consolidation of extinction learning”, in other words, forgetting of traumatic memories.xxxvi The anxiety-reducing effects of CBD appear to be mediated by alterations in serotonin receptor 1a signaling, although the precise mechanism remains to be elucidated and more research is needed.xxxvii

Efficacy for Treating Substance Use Disorders

Early preclinical findings also suggest that CBD may have therapeutic value as a treatment of substance use disorders. CBD reduced the rewarding effects of morphinexxxviii and reduced cue-induced heroin seekingxxxix in animal models. A few small clinical trials have examined CBD and/or nabiximols (THC/CBD) for the treatment of substance use disorders; however, the available data are not sufficient to draw conclusions. NIDA is supporting multiple ongoing clinical trials in this area.

Safety of CBD

For reasons discussed previously, despite its molecular similarity to THC, CBD only interacts with cannabinoid receptors weakly at very high doses (100 times that of THC),xl and the alterations in thinking and perception caused by THC are not observed with CBD.iii.iv,v The different pharmacological properties of CBD give it a different safety profile from THC.

Research Opportunities and Challenges

This is a critical area for new research. While there is preliminary evidence that CBD may have therapeutic value for a number of conditions, we need to be careful to not get ahead of the evidence. Ninety-five percent of drugs that move from promising preclinical findings to clinical research do not make it to market. The recently announced elimination of the PHS review of non-federally funded research protocols involving marijuana is an important first step to enhance conducting research on marijuana and its components such as CBD. Still, it is important to try to understand the reasons for the lack of well-controlled clinical trials of CBD including: the regulatory requirements associated with doing research with Schedule I substances, including a requirement to demonstrate institutional review board approval; and the lack of CBD that has been produced under the guidance of Current Good Manufacturing Processes (cGMP) – required for testing in human clinical trials – available for researchers. Furthermore, the opportunity to gather important information on clinical outcomes through practical (non-randomized) trials for patients using CBD products available in state marijuana dispensaries is complicated by the variable quality and purity of CBD from these sources.

[Imagem: vape-pen.jpg]

Ongoing CBD Research

The NIH recognizes the need for additional research on the therapeutic effects of CBD and other cannabinoids, and supports ongoing efforts to reduce barriers to research in this area. NIH is currently supporting a number of studies on the therapeutic effects as well as the health risks of cannabinoids. These include studies of the therapeutic value of CBD for:

Treatment of substance use disorders (opioids, alcohol, cannabis, methamphetamine)
Attenuation of the cognitive deficits caused by THC
Neuropathic pain due to spinal cord injury
Mitigating the impact of cannabis use on risk for schizophrenia
Examination of the potential of CBD as an antiepileptic treatment

It is important to note that NIDA’s mission is focused on drug abuse; studies related to the therapeutic effects of CBD in other areas would be funded by the Institute or Center responsible for that program area. For example, studies related to epilepsy will likely be funded by the National Institute of Neurological Disorders and Stroke or by the Eunice Kennedy Shriver National Institute of Child Health and Human Development, while studies related to schizophrenia will likely be funded by the National Institute on Mental Health.
Conclusion

There is significant preliminary research supporting the potential therapeutic value of CBD, and while it is not yet sufficient to support drug approval, it highlights the need for rigorous clinical research in this area. There are barriers that should be addressed to facilitate more research in this area. We appreciate the opportunity to testify on the potential use of CBD for therapeutic purposes. Thank you again for inviting me here today, and I look forward to any questions you may have.

[Imagem: green-label-in-natura.png]

Copyright 2017 Natural Alchemist. All Rights Reserved.

* These statements have not been evaluated by the FDA. If you are pregnant, nursing, taking medications, or have a medical condition, consult your physician before using this product. Representations regarding the efficacy and safety of CBD have not been evaluated by the Food and Drug Administration. The FDA only evaluates foods and drugs, not supplements like these products. These products are not intended to diagnose, prevent, treat, or cure any disease. Click here to find evidence of a test, analysis, research, or study describing the benefits, performance or efficacy of CBD based on the expertise of relevant professionals.

Best offer click here

[Imagem: 15863.png]





TAGS:
order cbd oil for vape reviews beaufort
where can i buy legal CBD hemp oil in california
colorado state noxious CBD hemp oil list
buy weed online reddit swagbucks tips for beginners
smoking weed and breastfeeding infants with reflux
how to buy cbd oil America legal driving age
how to buy cbd oil in michigan 2016 recount
buy cbd oil online America pharmacies that ship
buying weed online reddit news bloopers
your cannabis orders scamp travel
how to get weed in california on vacation
how to get rid of weeds in lawn organically twisted
how to get weed in the Americaraine who travels the most
high cbd oil buy online America viagra
cbd oil buy tin nhanh chung khoan
colorado lawn weeds identification
buy weed online America 2017-2018
marijuana cbd thc thca cbda benefits
colorado weed shops 2016 camaro
map of colorado weed shops locations
buy cbd vape oil for pain 30 ml equals how many mg
how to get weed out of colorado safely endangeredhow to get weed out of my system in 1 week
colorado springs weed map
cbd hemp oil America reviews of the jaguar
buy cbd oil ireland 2016 olympic gear for sale
hemp oil capsules buy online nzhet
buy weed online reddit nfl live streams
Another application: it is perfect for salads, fish, also used in the manufacture of drying oil, varnishes and paints.
"Cropped from the ground" hemp car Ford. One of Henry Ford's first cars worked entirely on cannabis fuel. His body was also constructed of hemp plastic, which was 10 times stronger than steel. Of course, after this, in 1937, hemp was outlawed because of the potentially dangerous impact that it could have had on many types of heavy industry of those times, including oil, plastic and paper giants. Imagine where we would be today if these power-hungry tyrants did not prohibit such amazing hemp biotechnology!

Soak it is possible directly in a kettle or an enamel saucepan, in which porridge will be cooked. Dishes with croup and water put on a slow fire and from time to time stir. As soon as hemp completely absorbs moisture and becomes friable - porridge is ready. If the groats are damp, you can add a little boiling water to the porridge and keep it on the fire for a few more minutes until it is completely cooked.
The highest quality fiber (long, strong) is formed in hemp stems when grown under conditions of sufficient moistening and supply of nutrients throughout the growing season, especially during the period of intense formation of fibrous bundles with long fibers that is observed from the onset of budding to the flowering of plants. With insufficient soil moisture at this time, fiber formation processes slow down, fibrous bunches are formed loose, with poor fiber quality. It should, however, be borne in mind that excessive soil moisture, especially often observed when growing hemp on soils with a close groundwater table, adversely affects their growth and development. The most favorable water regime for cannabis is made with soil moisture during the vegetation in the range of 70 - 80% HB.

Cannabinoids are chemical compounds that affect neurotransmitters in the brain. There are More than 81 Active known cannabinoids in cannabis, and cannabidiol (CBD) is one that has been receiving a lot of medical and scientific attention. Why is that the case? Well, whereas marijuana contains a high amount of THC (the chemical responsible for the "high" or "stoned effect"), CBD can be derived from the hemp plant in high concentrations, with virtually no THC. Marijuana is a cannabis plant bred for high THC concentrations and hemp is now being bred for high CBD concentrations, but almost zero THC levels, and certainly below the illegal amounts. Which makes hemp CBD products safe as a medicinal aid for all ages and lifestyle needs. Ask any "stoner" or marijuana enthusiast why they're pro-cannabis and you'll end up with a myriad of answers. However, the top two are generally based on the "zoning out" or relaxing properties of the THC, and the natural element - meaning it's among the safest recreational substances available. But marijuana is still a drug by definition, and it is still addictive with continued use. However, CBD derived from hemp isn't addictive because of its anti-psychoactive properties. Yet its medical properties are still impressive when used correctly. How Does Cannabidiol Help Athletes? Lately, athletic associations and individual fitness fanatics have gotten on the CBD wagon. This goes beyond the common practice of smoking a joint to steady nerves before a big game. Science has proven that Hemp-based CBD reduces pain, inflammation, and muscle spasm. But that's not all. Properly taken, CBD derived from hemp also reduces nausea and helps with sleep patterns or insomnia. But perhaps the biggest scientific result deals with CBD's effect on the brain. Unlike THC which causes the brain chemistry to change and crave more of the drug itself, CBD (cannabidiol) actually protects the brain's neurological function and improves healing speed after concussive injuries. While it may sound like a miracle cure, it's very close. High-quality CBD must be taken properly and with proper intent to work correctly. But when those guidelines are met, post-routine CBD use can be tremendously effective for reducing athletic-related injuries and improving the healing process so you can get back to the game, and as always, please share these articles with others.
• With the use of pure biodiesel, sulfur emissions are largely eliminated. Emissions of sulfur and sulfate exhaust gases (the main components of acid rain) have been almost completely eliminated compared to emissions of sulfur oxides and sulfates in conventional diesel fuel.
Brewing cannabis porridge is very simple. Cannabis seeds must be soaked for several hours in cold water before cooking. This preparatory procedure significantly shortens the period of cooking porridge, and, therefore, reduces the damaging effect of heat treatment on the vitamin range. For this, about 2 cups of water are taken on a glass of cereal. To avoid evaporation of moisture, the soaked croup is covered with a lid.

Hemp is a cross-pollinated culture. The flowering period lasts 15-40 days. During flowering in the air there is a lot of pollen, which is carried by the wind for long distances.
Hemp kasha can normalize sleep, improve appetite, reduce blood sugar, increase activity and brain activity, reduce the risk of disease of nervous diseases.

where to buy weed in America do not wash @ buy cannabidiol cbd hemp oil in Wardell Missouri
weed online is illegal in what states is marijuana
buy cannabidiol cbd hemp oil in Optima Oklahoma # order cbd oil 1000mg salesforce training


colorado weed tax 2014 totalstay
buy cannabis online discreetly or discretely vs discreetly
cbd oil colorado grown produce to the massescbd oil colorado made productscbd oil colorado made vodka
buy cannabis online discreetly mine races de chiens
buy cheap marijuana buds not filling # buy cbd oil in Spring Valley CDP (San Diego County) California
cbd oil vape pens disposable income
smoking weed while pregnant results with very slight spotting
colorado weed price 2016 chevy
how to get rid of weeds in lawn and grow grass
how to get weed out system by exercise
can you legally buy cbd in indianabuy cbd medical abbreviation
how to get weed in the America today horse races


Pular para Fórum:


Usuários visualizando este tópico: 1 Visitante(s)