Avaliação do Tópico:
  • 0 Voto(s) - 0 em Média
  • 1
  • 2
  • 3
  • 4
  • 5
colorado weed shops 2016 camaro
#1
colorado weed shops 2016 camaro

We offer CBD Hemp related products providing the best potencies and purity of Cannabidiol (CBD) products available nationwide. Our mission is to educate and promote natural therapies as part of our approach to optimum health and wellness. We have various products to suit the multiple needs and conditions of our clients.

[Imagem: Buy-Now-Button.png]

===>Delivery of the product to all states of America<===

[Imagem: 15864.png]

"Cannabidiol: Barriers to Research and Potential Medical Benefits"

Mr. Chairman, Ms. Chairwoman, and Members of the Senate Drug Caucus, thank you for inviting the National Institute on Drug Abuse (NIDA), a component of the National Institutes of Health (NIH), to participate in this hearing to share what we know about the biology and the potential therapeutic effects of cannabidiol (CBD), one of the main active chemical compounds found in marijuana. In light of the rapidly evolving interest in the potential use of marijuana and its derivative compounds for medical purposes, it is important to take stock of what we know and do not know about the therapeutic potential of CBD.

[Imagem: click-here-to-purchase-with-cbd-bottle.j...;amp;h=626]

Background

To date, 23 states and the District of Columbia have passed laws allowing marijuana to be used for a variety of medical conditions. Fifteen additional states have enacted laws intended to allow access to CBD oil and/or high-CBD strains of marijuana. Interest in the potential therapeutic effects of CBD has been growing rapidly, partially in response to media attention surrounding the use of CBD oil in young children with intractable seizure disorders including Dravet syndrome and Lennox-Gastaut syndrome. While there are promising preliminary data, the scientific literature is currently insufficient to either prove or disprove the efficacy and safety of CBD in patients with epilepsy.i and further clinical evaluation is warranted. In addition to epilepsy, the therapeutic potential of CBD is currently being explored for a number of indications including anxiety disorders, substance use disorders, schizophrenia, cancer, pain, inflammatory diseases and others. My testimony will provide an overview of what the science tells us about the therapeutic potential of CBD and of the ongoing research supported by NIH in this area.
CBD Biology and Therapeutic Rationale


[Imagem: 15862.png]

Neuroprotective and Anti-Inflammatory Effects

CBD has also been shown to have neuroprotective properties in cell cultures as well as in animal models of several neurodegenerative diseases, including Alzheimer’s,xii,xiii,xiv stroke,xv glutamate toxicity,xvi multiple sclerosis (MS),xvii Parkinson’s disease,xviii and neurodegeneration caused by alcohol abuse.xix Nabiximols (trade name Sativex), which contains THC and CBD in roughly equal proportions, has been approved throughout most of Europe and in a number of other countries for the treatment of spasticity associated with MS. It has not been approved in the United States, but clinical trials are ongoing, and two recent studies reported that nabiximols reduced the severity of spasticity in MS patients.xx,xxi There have been limited clinical trials to assess the potential efficacy of CBD for the other indications highlighted; however, a recent small double-blind trial in patients with Parkinson’s disease found the CBD improved quality-of-life scores.xxii

Analgesic Effects

There have been multiple clinical trials demonstrating the efficacy of nabiximols on central and peripheral neuropathic pain, rheumatoid arthritis, and cancer pain.xxiii In addition, nabiximols is currently approved in Canada for the treatment of central neuropathic pain in MS and cancer pain unresponsive to opioid therapy. However, the current evidence suggests that the analgesia is mediated by THC and it is unclear whether CBD contributes to the therapeutic effects.xxiv THC alone has been shown to reduce pain;xxv,xxvi we are unaware of clinical studies that have explored the efficacy of CBD alone on pain. However, the anti-inflammatory properties of CBD (discussed above) could be predicted to play a role in the analgesic effects of nabiximols. Recent research has also suggested that cannabinoids and opioids have different mechanisms for reducing pain and that their effects may be additive, which suggests that combination therapies may be developed that may have reduced risks compared to current opioid therapies. However, this work is very preliminary.xxvii

Anti-Tumor Effects

In addition to the research on the use of cannabinoids in palliative treatments for cancer—reducing pain and nausea and in increasing appetite—there are also several pre-clinical reports showing anti-tumor effects of CBD in cell culture and in animal models.xxviii These studies have found reduced cell viability, increased cancer cell death, decreased tumor growth, and inhibition of metastasis (reviewed in McAllister et al, 2015).xxix These effects may be due to the antioxidant and anti-inflammatory effects of CBD;xxx however these findings have not yet been explored in human patients. There are multiple industry sponsored clinical trials underway to begin to test the efficacy of CBD in human cancer patients.

Anti-Psychotic Effects

Marijuana can produce acute psychotic episodes at high doses, and several studies have linked marijuana use to increased risk for chronic psychosis in individuals with specific genetic risk factors. Research suggests that these effects are mediated by THC, and it has been suggested that CBD may mitigate these effects.xxxi There have been a few small-scale clinical trials in which patients with psychotic symptoms were treated with CBD, including case reports of patients with schizophrenia that reported conflicting results; a small case study in patients with Parkinson’s disease with psychosis, which reported positive results; and one small randomized clinical trial reporting clinical improvement in patients with schizophrenia treated with CBD.xxxii Large randomized clinical trials would be needed to fully evaluate the therapeutic potential of CBD for patients with schizophrenia and other forms of psychosis.

[Imagem: Gold-RSHO-tubes-720h-copy.png]

Buy CBD online from UK supplier of CBD Oil, CBD Brothers Oil Also available CBD Balm, 100% Organic - High CBD. CBD Brothers High Concentration CBD ...
Legislation allowing the use of low-THC, CBD-rich marijuana oil primarily for children suffering from seizure disorders has been approved in ...

[Imagem: Visit-Website-Button.png]

Anti-Anxiety Effects

CBD has shown therapeutic efficacy in a range of animal models of anxiety and stress, reducing both behavioral and physiological (e.g., heart rate) measures of stress and anxiety.xxxiii,xxxiv In addition, CBD has shown efficacy in small human laboratory and clinical trials. CBD reduced anxiety in patients with social anxiety subjected to a stressful public speaking task.xxxv In a laboratory protocol designed to model post-traumatic stress disorders, CBD improved “consolidation of extinction learning”, in other words, forgetting of traumatic memories.xxxvi The anxiety-reducing effects of CBD appear to be mediated by alterations in serotonin receptor 1a signaling, although the precise mechanism remains to be elucidated and more research is needed.xxxvii

Efficacy for Treating Substance Use Disorders

Early preclinical findings also suggest that CBD may have therapeutic value as a treatment of substance use disorders. CBD reduced the rewarding effects of morphinexxxviii and reduced cue-induced heroin seekingxxxix in animal models. A few small clinical trials have examined CBD and/or nabiximols (THC/CBD) for the treatment of substance use disorders; however, the available data are not sufficient to draw conclusions. NIDA is supporting multiple ongoing clinical trials in this area.

Safety of CBD

For reasons discussed previously, despite its molecular similarity to THC, CBD only interacts with cannabinoid receptors weakly at very high doses (100 times that of THC),xl and the alterations in thinking and perception caused by THC are not observed with CBD.iii.iv,v The different pharmacological properties of CBD give it a different safety profile from THC.

Research Opportunities and Challenges

This is a critical area for new research. While there is preliminary evidence that CBD may have therapeutic value for a number of conditions, we need to be careful to not get ahead of the evidence. Ninety-five percent of drugs that move from promising preclinical findings to clinical research do not make it to market. The recently announced elimination of the PHS review of non-federally funded research protocols involving marijuana is an important first step to enhance conducting research on marijuana and its components such as CBD. Still, it is important to try to understand the reasons for the lack of well-controlled clinical trials of CBD including: the regulatory requirements associated with doing research with Schedule I substances, including a requirement to demonstrate institutional review board approval; and the lack of CBD that has been produced under the guidance of Current Good Manufacturing Processes (cGMP) – required for testing in human clinical trials – available for researchers. Furthermore, the opportunity to gather important information on clinical outcomes through practical (non-randomized) trials for patients using CBD products available in state marijuana dispensaries is complicated by the variable quality and purity of CBD from these sources.

[Imagem: vape-pen.jpg]

Ongoing CBD Research

The NIH recognizes the need for additional research on the therapeutic effects of CBD and other cannabinoids, and supports ongoing efforts to reduce barriers to research in this area. NIH is currently supporting a number of studies on the therapeutic effects as well as the health risks of cannabinoids. These include studies of the therapeutic value of CBD for:

Treatment of substance use disorders (opioids, alcohol, cannabis, methamphetamine)
Attenuation of the cognitive deficits caused by THC
Neuropathic pain due to spinal cord injury
Mitigating the impact of cannabis use on risk for schizophrenia
Examination of the potential of CBD as an antiepileptic treatment

It is important to note that NIDA’s mission is focused on drug abuse; studies related to the therapeutic effects of CBD in other areas would be funded by the Institute or Center responsible for that program area. For example, studies related to epilepsy will likely be funded by the National Institute of Neurological Disorders and Stroke or by the Eunice Kennedy Shriver National Institute of Child Health and Human Development, while studies related to schizophrenia will likely be funded by the National Institute on Mental Health.
Conclusion

There is significant preliminary research supporting the potential therapeutic value of CBD, and while it is not yet sufficient to support drug approval, it highlights the need for rigorous clinical research in this area. There are barriers that should be addressed to facilitate more research in this area. We appreciate the opportunity to testify on the potential use of CBD for therapeutic purposes. Thank you again for inviting me here today, and I look forward to any questions you may have.

[Imagem: endoca-drops.png]

Copyright 2017 Natural Alchemist. All Rights Reserved.

* These statements have not been evaluated by the FDA. If you are pregnant, nursing, taking medications, or have a medical condition, consult your physician before using this product. Representations regarding the efficacy and safety of CBD have not been evaluated by the Food and Drug Administration. The FDA only evaluates foods and drugs, not supplements like these products. These products are not intended to diagnose, prevent, treat, or cure any disease. Click here to find evidence of a test, analysis, research, or study describing the benefits, performance or efficacy of CBD based on the expertise of relevant professionals.

Best offer click here

[Imagem: 15863.png]





TAGS:
buy cbd oil capsules
buy weed eater trimmer featherlite # cbd oil for sale Downsville New York
buy cbd online in Spruce Pine North Carolina @ buy cbd oil online reddit swagbucks forum
how to buy cbd oil America legal pistols
hemp seed oil buy online East Cape Girardeau Illinois # how to get weed in the America hexham horseless carriages for sale
how to get weed out of your system fast naturally
cheap cbd oils for vaporizers reviews
cbd oil vape atomizer stands and racks
buy thc edibles online shipped traduction reverso
cbd cancer fighting youtube addiction understanding science
cheap feminized marijuana seeds for sale in usa
marijuana cbd meaning cannabis sativa vs cannabis
cheap high cbd marijuana tincture dose
can you buy hemp oil for cancer online activity
how to get rid of weeds in lawn America
buy cbd oil charlotte's web worksheets by chapter 6
cbd hemp vs marijuana
medicinal cbd oil buy colorado & company show wedding
buy medical grade cbd oil for epilepsy
how much weed to buy to start selling lularoe ruined
buy cbd vape liquids for sale
cbd oil killing cancer not people amazon
best weed killer reviews 2016 infiniti
cbd oil colorado springs dispensary hours in colorado
cbd cancer fighting youtube addiction causedcbd cancer fighting youtube videoscbd cancer fighting youtube
places to buy weed in colorado springs
where to buy phoenix tears hemp oilbuy hemp oil phoenix tears pancreatic cancerbuy hemp oil phoenix tears rick
Hassan said Koster’s office agreed to drop the suit after he agreed to stop selling CBD.
Scott Sizer was diagnosed with multiple sclerosis in 1990. He uses a wheelchair and has regular muscle spasms.

“Believe me, I have vetted this,” Sanders said. “Our first year we spent more on legal fees than anything.”
Producers of pure products were forced out of the market, mutually exclusive, mutants. Cannabis while no one has modified, it is created by nature brilliantly. This plant is very resistant to unfavorable factors and insects. The only "enemy" of the man growing hemp grain is the feathered one, but the seeds are so carefully hidden in the inflorescences that most of them still remain untouched.

Summary of Dr. Rob Silver's Book on Cannabis and CBD for Pets: As of the fall of 2016, 25 states and the District of Columbia allow for the medicinal use of marijuana prescribed by physicians, for human patients. Many pet owners in these states are wondering if it might also be helpful for their dogs or cats with intractable epilepsy, or cancer, or arthritis, anxiety, appetite, nausea and more. This book helps to answer those questions. It presents a balanced approach to understand how the herb cannabis works in the human and animal body, and what possible problems might arise with its use. The book very specifically advises pet owners how to avoid these problems, and still provide their pets with relief. The legalities of the use of medical marijuana in pets is discussed in this book, so pet owners can understand that no matter how much a veterinarian might want to help a patient be free from pain or suffering, because the Federal government has marijuana categorized as a Schedule One Controlled Substance, meaning that it has no recognized medical uses, it is illegal for a vet to prescribe it. They might lose their license if they did. This book does not advise pet owners who live in states where there is not medical marijuana for people to break the law and give their pets an illegal substance in their state.
Cannabinoids are chemical compounds that affect neurotransmitters in the brain. There are More than 81 Active known cannabinoids in cannabis, and cannabidiol (CBD) is one that has been receiving a lot of medical and scientific attention. Why is that the case? Well, whereas marijuana contains a high amount of THC (the chemical responsible for the "high" or "stoned effect"), CBD can be derived from the hemp plant in high concentrations, with virtually no THC. Marijuana is a cannabis plant bred for high THC concentrations and hemp is now being bred for high CBD concentrations, but almost zero THC levels, and certainly below the illegal amounts. Which makes hemp CBD products safe as a medicinal aid for all ages and lifestyle needs. Ask any "stoner" or marijuana enthusiast why they're pro-cannabis and you'll end up with a myriad of answers. However, the top two are generally based on the "zoning out" or relaxing properties of the THC, and the natural element - meaning it's among the safest recreational substances available. But marijuana is still a drug by definition, and it is still addictive with continued use. However, CBD derived from hemp isn't addictive because of its anti-psychoactive properties. Yet its medical properties are still impressive when used correctly. How Does Cannabidiol Help Athletes? Lately, athletic associations and individual fitness fanatics have gotten on the CBD wagon. This goes beyond the common practice of smoking a joint to steady nerves before a big game. Science has proven that Hemp-based CBD reduces pain, inflammation, and muscle spasm. But that's not all. Properly taken, CBD derived from hemp also reduces nausea and helps with sleep patterns or insomnia. But perhaps the biggest scientific result deals with CBD's effect on the brain. Unlike THC which causes the brain chemistry to change and crave more of the drug itself, CBD (cannabidiol) actually protects the brain's neurological function and improves healing speed after concussive injuries. While it may sound like a miracle cure, it's very close. High-quality CBD must be taken properly and with proper intent to work correctly. But when those guidelines are met, post-routine CBD use can be tremendously effective for reducing athletic-related injuries and improving the healing process so you can get back to the game, and as always, please share these articles with others.
He said he’s placed about a half-dozen calls to Hawley’s office to ask if there’s been some policy change.

The answer was not so simple.
According to the publication "Popular Mechanics", the first Model-T car Henry Ford was designed to work on diesel fuel from cannabis, and even self-made was made of KONOPLI! Ford was photographed in his big estate among his own hemp fields. The car, which "grew out of the ground," had plastic panels of hemp, the impact strength of which was ten times higher than the strength of steel. Imagine that you are driving a machine made from plant fibers, which, moreover, works on vegetable-based fuel!

buy cannabidiol cbd hemp oil in Mariaville Lake New York @ buy thc edibles online shipped legal marijuana
best cbd oil cheap
buy thc edibles online uke


buy weed online 2016 census population
buy cbd hemp oil for sale America
how to buy cbd oil in michigan 2016 presidential results michigan
cbd oil vape atomizer velocity equation
hemp seed oil buy online Fayetteville Alabama @ buy cbd concentrate vape oil pens
buy legal weed massachusetts burn permits montana # cbd oil for sale Platinum Alaska
smoking weed while pregnant studies show meme
cbd oil buyers
cbd oil colorado springs dispensary directory opus
how much weed to buy for 5$ itunes cards
marijuana cbd thc thca cbda auditions shoes
medicinal marijuana cbd benefits testimonials for real estate


Pular para Fórum:


Usuários visualizando este tópico: 1 Visitante(s)